Restriction Enzymes
Enzo Life Sciences ODN 2006 (TLRGRADE™) (synthetic) (BULK) (1mg)
CpG oligodeoxynucleotide (Type B) with phosphorothioate backbone. Specific ligand for human and mouse TLR9 (Toll-like receptor 9). Formulation: Lyophilized. Sterile. Long Term Storage: +4°C.
New England Biolabs, Inc. Nb.BsrDI – 5000 units
A restriction endonuclease that recognizes the sequence GCAATG_NN.
AURORA BIOLABS LLC Human Malic enzyme 3 (ME3),100 μg
ME3 is another isoform of malic enzyme that is found in various tissues in the human body. This gene encodes a mitochondrial NADP(+)- dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Its exact biochemical significance may vary depending on the tissue or cell type in which it is expressed.
ABclonal Technology BstEII
5...G/ G T N A C C...3 3...C C A N T G/ G...5 Isoschizomers: Eco91I BstPI EcoO65I PspEI
Cayman Chemical BAM-22Phumnmouseratb 5mg
An endogenous neuropeptide derived from proenkephalin A; expressed in the adrenal medulla and at lower concentrations throughout the brain; binds the µ-, κ-, and δ-opioid receptors (Kis = 0.9, 2.9, and 7.2 nM, respectively); intracerebroventricular administration induces analgesia in a tail-flick assay in mice (ED50 = 6.4 nM); decreases the frequency of tail flicking, as well as paw lifting and licking in a rat model of formalin-induced nocifensive behavior at 5 nM/animal
Apexbio Technology LLC EZ Cap Nuc-mScarlet Probe mRNA (m1Ψ) 5x1mg (1mg/mL)
Nuc-mScarlet mRNA encodes a fusion protein combining a nuclear localization signal (Nucleus-targeting signal) with the fluorescent protein mScarlet By fusing mScarlet with a nuclear localization signal it enables the monitoring of dynamic processes inside the nucleus in living cells in real-time Nuc-mScarlet exhibits high photostability and brightness making it particularly suitable for long-term imaging experiments Moreover the spectral properties of mScarlet are compatible with other fluorescent proteins such as GFP facilitating multiplex labeling experiments EZ Cap Nuc-mScarlet Probe mRNA (m1 ) is provided at 1 mg/mL specifically designed for nuclear-targeted expression of red fluorescent protein labels This mRNA is synthesized through co-transcriptional capping resulting in a Cap 1 structure The incorporation of m1 modifications poly(A) tail significantly enhances mRNA stability and lifetime both in vitro and in vivo
Apexbio Technology LLC Dpn I(Synonyms: DpnI, DpnI Restriction Enzyme, Dam methylation-sensitive restriction enzyme DpnI), 500U.
Dpn I is a restriction endonuclease sensitive to Dam methylation specifically recognizing and cleaving the adenine N6-methylated sequence GA/TC within DNA Cleavage is dependent on adenine methylation status mammalian CpG methylation overlapping Dpn I sites blocks cleavage and methylation by Dcm is not recognized by this enzyme It is routinely used for the rapid digestion of plasmid DNA PCR fragments and genomic DNA and finds broad utility in genetic typing molecular cloning Southern blotting SNP genotyping and restriction fragment length polymorphism (RFLP) analyses
Cayman Chemical BAM-22P8-22humnmouse1mg
A neuropeptide and MRGPRX1 agonist; induces calcium mobilization in HEK293S cells expressing human MRGPRX1 or SNSR3 (EC50s = 14 and 28 nM, respectively); inhibits voltage-induced calcium currents in isolated rat neurons expressing human MRGPRX1 (EC50 = 0.6 µM); intrathecal administration decreases the tail-flick latency in pertussis toxin-stimulated rats and increases the tail-flick latency in U-73122-stimulated rats, indicating changes in pain sensitivity, at 30 nmol/animal; increases scratching behavior in wild-type mice and enhances bile-duct ligation-induced scratching behavior in a mouse model of cholestasis